| Home :: Infrastructure :: Instrumentation and Facilities |
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| Instrumentation and Facilities |
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| The R&D center in Mumbai measures 20,000 sq ft in area, of which 6000 sq ft
of laboratory space has been re-furbished for discovery operations. |
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| Synthetic Chemistry : |
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- Fully equipped Laboratory space of 6000 sq. feet expandable to 40000 sq.feet with modular Fuming hoods for all scientists.
- Rotary evaporators.
- Autoclaves.
- Paar Hydrogenators.
- High Vacuum pumps (0.005 mm).
- 50 liter jacketed reactor (-60°C- + 200°C).
- 100 liter jacketed reactor (-60°C- + 200°C).
- Huber unistat cooling and heating systems (-90°C- + 200°C).
- 20 liter Buchi Rotary evaporators.
- ISCO 16X Combiflash Companion systems.
- Agilent single quad LC-MS for reaction monitoring.
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| Analytical Chemistry : |
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| Kemxtree has state of art in house analytical instrumentation to support the research activities which includes |
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- Bruker Avance III 400 MHz NMR (2008 model) with 24 sample auto-sampler
to record 1H, 13C, 15N, Phosphorus and fluorine nuclei. Variable temperature
experiments from - 60°C to + 80°C can also be conducted.
- Agilent LC Mass systems for purification and reaction monitoring.
- FT-IR and digital polarimeter.
- Varian Preparative HPLC with 500ml/min pump head for large scale
purification.
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| In Vitro Drug Metabolism : |
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- Two Triple Quad tandem LC-MS systems for Bio-analytical quantification;
An AGILENT 6310 QQQ in tandem with rapid resolver Agilent HPLC and a SCIEX ABI 2000 in tandem with rapid resolver Agilent HPLC.
- Ion-trap MS for Metabolite Identification an Agilent 6410 ion trap in tandem with rapid resolver Agilent HPLC.
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